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Jul 09, · Side effects; Interactions; FAQ; What is amitriptyline? Amitriptyline is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood. Amitriptyline is a prescription medicine used to treat symptoms of depression. Risk of anticholinergic side effects; may cause constipation, urinary retention, blurred vision, and xerostomia. Use caution in patients with urinary retention, open-angle glaucoma, BPH, decreased gastrointestinal motility, or paralytic ileus. Possibility of EPS and neuroleptic malignant syndrome.
Medically reviewed by Sanjai Sinha, MD. Last updated on July 9, Amitriptyline is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers neurotransmitters that communicate between brain cells and help regulate mood.
Amitriptyline is a prescription medicine used to treat symptoms of depression. You should not use amitriptyline if you have recently had a heart attack.
Do not use amitriptyline if you have used an MAO inhibitor in the past 14 days, such as isocarboxazidlinezolidmethylene blue injection, phenelzinerasagilineselegilineor tranylcypromine. You may have thoughts about suicide when you first start taking an antidepressant such as amitriptyline, especially if you are younger than dffects years old.
Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive mentally or physicallymore depressed, or have amitriptylinf about suicide or hurting yourself. Do not use amitriptyline if you have used an MAO inhibitor in the past 14 days.
A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopramescitalopramfluoxetine Prozacfluvoxamine evfects, paroxetinesertraline Zolofttrazodoneor vilazodone. Some young people have thoughts about suicide when first taking how to make an remote control helicopter antidepressant.
Your doctor should check your progress efects regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Take amitriptyline exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. It may take up to 4 weeks before your symptoms improve.
Keep using the medication as directed and tell your doctor if your symptoms do not improve. If you need surgery, tell your surgeon you currently use amitriptyline. Amitriptylinw may need to stop for a short time. Do not stop using amitriptyline suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using amitriptyline. Store at room temperature away from moisture and heat.
Keep the bottle tightly closed when not in use. Use: Relief of symptoms of depression. Take the medicine as soon as you can, but evfects the missed dose if it is almost time for your next dose.
Do not take two doses at one amitriptylune. Seek emergency medical attention or call the Poison Help line at An overdose of amitriptyline can sdie fatal. Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma. Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with amitriptyline. Avoid driving or hazardous activity until you know how amitriptyline will affect you.
Your reactions could be impaired. If exposure to sunlight or tanning beds. Amitriptyline can make you sunburn more easily. Wear protective clothing and use sunscreen SPF 30 or higher edfects you are outdoors. Get emergency medical help if you have signs of an allergic reaction to amitriptyline: hives ; 10mf breathing; swelling of your face, lips, tongue, or throat. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxietypanic how to do emojis on keyboardtrouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive mentally amitripptyline physicallymore depressed, or have thoughts about suicide or hurting yourself.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Taking amitriptyline with other drugs that make amifriptyline sleepy can worsen this effect. Ask your doctor before taking amitriptyline with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. Sometimes it what is a normal b12 blood level not safe to use certain efffects at the same time.
Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications 10mgg effective. This list is not complete. Other drugs may affect amitriptyline, including prescription and over-the-counter medicines, vitaminsand herbal xmitriptyline. Not all possible sife interactions are listed here. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use amitriptyline only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Detailed Amitriptyline dosage information. Amitriptyline side effects more detail. Amitriptyline drug interactions more detail. Drug Status Availability Prescription only Rx. Mylan Pharmaceuticals Inc. Sandoz Inc. Drug Class. Tricyclic antidepressants.
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Amitriptyline may induce side effects similar to other tricyclic antidepressants. Some of the below mentioned side effects e.g. headache, tremor, disturbance in attention, constipation and decreased libido may also be symptoms of depression and usually attenuate when the depressive state improves. side effects are less frequent. The most common side effects are drowsiness, blurred vision, dilated pupils, constipation, sweating, itching and dry mouth. Changes in behaviour have also occurred in children receiving amitriptyline. Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. After that, the side effects wore off, and it didn't feel like I was taking any medication at all. I have now been taking amitriptyline for two months at a current dosage of 25mg per day. While the side effects have subsided, I have not seen any improvement in my migraine frequency (20+ days/month) or severity.
Amitriptyline has an average rating of 7. Compare all 56 medications used in the treatment of Migraine Prevention. Then about 5 years ago the dizziness set in too. Diagnosed with migraine associated vertigo. Always felt dizzy, off balance, like walking on a boat.
My vision was always off like living in a dream state. Then I started amitriptylne 10mg. It has helped me tremendously. I was so nervous about starting it from reading all the side effects, but I had no side effects only benefits. My vision became clearer. The dizziness improved so much. Of course I will still have occasional dizziness like before my period sometimes, but nothing like what it was.
I also increased to 15mg because I started having night time panic attacks, and at 15mg those have significantly improved as well. It knocks me out within half hour of taking it, and even if I wake up in panic, I'm too sleepy to worry about it and just fall back asleep.
I have been on it for about 1 year and a half. Not planning to stop it for now. Started when I was 17 and I'm now I've tried so many meds for them but nothing works for very long, including this one. Amitriptyline helps for a month or so and then is pretty useless.
Each dose increase follows the same pattern, a month or so of less frequent migraines, then constant migraines again. I get migraines for days, one day off then migraine on the opposite side. Typically starts on my left side for a few days then after 1 day of relief it hits the right side.
I can predict when it will stop when it changes sides. I average 3 or more migraines a month, each one lasting days so I literally have more migraine days than no migraine days. Not to mention after it finally quits I'm exhausted so it takes another day to recoup.
Imitrex isn't much help either, within a few weeks of using it I reach the max dose for a 24 hr period without relief. Also it helped my IBS too! Go figure! Had some dry mouth when I first started taking it. I finally had an over the phone appointment with my doctor who said they were tension headaches.
She prescribed these amitript to prevent them. I had no idea that they were also used for anxiety or depression. I was nervous to try this for that exact reason but I was desperate for headache relief.
The first couple days I felt a little out of it but that went away. Until one day I was outside throwing a ball around with my daughter and realized that I was actually enjoying my life for once in a long time. I should mention my headaches have disappeared as well! Give it a try! I then switched family doctors to a new doctor who sent me for a CAT Scan and prescribed 10MG Amitriptyline after he saw the scan's results.
The migraines and headaches disappeared instantly and it has been a year now. I only have the dry mouth side effect. I began taking amitriptyline as a preventative 1 and a half years ago, while having more than 19 migraines per month. The preventative reduces my migraine down to about one or two migraines per month!! Just on 10mg my daily pain was reduced, and I found myself reaching for OTC pain killers only every 3rd day or so instead of daily.
It gave me clarity if mind, and I was able to process where I was feeling my pain more precisely, which was very valuable information for my doctor. Before taking this drug, my head pain was so bad I was unable to clarify where I was feeling it. I could not process it at all. I have since been bumped up to 20mg daily, and I things have improved even further.
I am able to spend afternoons and evenings with friends and family without reaching for pain killers. I am not as afraid of committing to plans in fear of an inevitable migraine. Being pain free in this regard is something I haven't felt in over a decade. I feel hope for the future knowing I don't have to spend my days in fear of pain. Truly incredible and life changing. A few years ago I just had the patterns and no pain then it changed to tension neck pain which which then turned into headache as soon as I woke up more or less daily.
Imigran helped but was popping them like smarties. I tried giving up all the known triggers but nothing helped then a couple of months ago Dr prescribed Amitriptyline 25mgs every night I have had maybe 2 or 3 slight headaches since. First week I was a little woozy but that passed. Now I wake up with a dry mouth and food tastes different but no headache. It used to be unusual to wake up with no headache now its unusual to wake up with one.
I recommend anyone to give it a try. I started at 5mg amitript and there was little improvement. I took 10mg on my own and that totally stopped all migraines. The only side effect I have had is dry-mouth, which can get unpleasant in speaking situations. Now I simply ensure that I have a bottle of water around. After trying so many migraine prevention medicines and other miscellaneous things ear piercings, stretches, pressure point therapy, etc. When I had to stop taking it for 3 months, they came back.
Once I started amitriptyline again, within day they were basically gone. It has changed my life in a tremendously positive way! I've had migraine almost all my life. I am This has been deeply affecting my quality of life, my relations mood changes and also at work.
The last neurologist I visited put me on Amitriptyline 25mg. The medicine helped a bit reducing the frequency of the migraines. However migraines came back and the last attack lasted for 3 weeks.
He changed the dose to 50 mg. I am now 71 days without migraine and still counting. I am a new person and I wish my comment may help others. Only taken half a 10mg tablet about 4. This has been life changing as I was getting a migraine headache every other day and sometimes every day for over 10 years. Wish I had known about this simple solution 10 years ago. All those days of agony and now I can plan my day without a blinking headache and feeling very ill with it.
Take as low a dose as feel necessary I was prescribed Elavil for headaches, irritable bowel syndrome, sleep trouble, back, neck, and arm pain. I've taken it for a week, and after one dose, the first thing I noticed was an awesome night's sleep, and no neck or jaw pain, pain on rising. I feel completely relaxed in the morning, a little drowsy but am able to function and get my three kids to school.
I have been taking it at 10pm and feel tired until noon, so I think I'm going to take it earlier in the evening. I haven't noticed any side effects at all. I am taking 10 mg. When I got the most recent pain, the doctors were quick to call it a migraine.
I felt like my head would explode, and I had none of the other side effects attributed to migraines. My doctor instead now calls it "severe head pain". I had it every other day for about a month. I actually called "" at one point because I thought I was dying the pain was so horrible. When I was first given elavil I was skeptical since it was touted as an "anit-depressant". I took it, and the first three days I actually had to take naps because it made me so sleepy.
On the fourth day I realized that although I still felt a little sleepy, I was now officially four days head pain free.
It has been a Godsend. I've tried to reduce the dosage but found the headaches returning. I haven't had a severe migraine with aura in months and I only get around 2 tension headaches a week extreme improvement. The only side effects that I've experienced are occasional constipation and heart palpitations.